※ GSK family introduction

    GSK (Glycogen synthase kinase 3) belong to CMGC family. Two isoforms have been identified in human genome, known as GSK3A and GSK3B. GSKs are highly conserved and have been found in nearly all eukaryote. Sequence analysis show that two genes display 85% sequence identity, and even higher in the catalytic domain (93%). Chromosomal mapping identified the cytological location of human GSK3A as 19q13.2, whereas human GSK3B maps to 3q13.3. Northern blot analysis shows that GSKs are expressed in different mammalian tissues. GSKs play an important role in a variety of cellular signaling pathways, including cellular proliferation, migration, inflammation and immue responses, glucose regulation and apoptosis (1).

Reference
3. Ali, A., Hoeflich, K.P. and Woodgett, J.R. (2001) Glycogen synthase kinase-3: properties, functions, and regulation. Chem Rev, 101, 2527-2540. PMID: 11749387

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Sol-0234	Solyc02g086670.2	K4BBH5
2		iEKPD-Sol-0660	Solyc06g082640.2	K4CAB9
3		iEKPD-Sol-0947	Solyc10g037910.1	K4CZB4
4		iEKPD-Sol-0723	Solyc07g055200.2	K4CG59	101244391
5		iEKPD-Sol-0169	Solyc02g072300.2	K4B8K4	101249039
6		iEKPD-Sol-0276	Solyc03g006070.2	K4BE30	101249608
7		iEKPD-Sol-0054	Solyc01g091620.2	K4AZA2	101258488
8		iEKPD-Sol-0077	Solyc01g101000.2	K4B1D0	101259887
9		iEKPD-Sol-0559	Solyc05g051050.2	K4C1D7	101263118
10		iEKPD-Sol-0085	Solyc01g103430.2	K4B1R9	101265073
11		iEKPD-Sol-1132	Solyc12g062870.1	K4DGB0	101266803