Vitis vinifera      CMGC/GSK


※ GSK family introduction

    GSK (Glycogen synthase kinase 3) belong to CMGC family. Two isoforms have been identified in human genome, known as GSK3A and GSK3B. GSKs are highly conserved and have been found in nearly all eukaryote. Sequence analysis show that two genes display 85% sequence identity, and even higher in the catalytic domain (93%). Chromosomal mapping identified the cytological location of human GSK3A as 19q13.2, whereas human GSK3B maps to 3q13.3. Northern blot analysis shows that GSKs are expressed in different mammalian tissues. GSKs play an important role in a variety of cellular signaling pathways, including cellular proliferation, migration, inflammation and immue responses, glucose regulation and apoptosis (1).

Reference
3. Ali, A., Hoeflich, K.P. and Woodgett, J.R. (2001) Glycogen synthase kinase-3: properties, functions, and regulation. Chem Rev, 101, 2527-2540. PMID: 11749387


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Viv-0461
VIT_07s0005g02100
D7U2N9
VIT_07s0005g02100
2
iEKPD-Viv-0653
VIT_10s0003g01480
D7TJN3
VIT_10s0003g01480
3
iEKPD-Viv-0780
VIT_12s0028g01810
F6H523
VIT_12s0028g01810
4
iEKPD-Viv-0813
VIT_12s0035g01060
D7TGS5
VIT_12s0035g01060
5
iEKPD-Viv-0923
VIT_14s0060g00600
D7UA83
VIT_14s0060g00600
6
iEKPD-Viv-0929
VIT_14s0066g01050
D7TWM5
VIT_14s0066g01050
7
iEKPD-Viv-0989
VIT_15s0048g02010
D7U7I5
VIT_15s0048g02010