※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (2)  or Unreviewed (4) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Ast-0146	CADATEAG00009858	Q0D0P5	hog1
2		iEKPD-Ast-0096	CADATEAG00006482	Q0CIC7	mpkC
3		iEKPD-Ast-0149	CADATEAG00010151	Q0D188	ATEG_00296
4		iEKPD-Ast-0136	CADATEAG00009562	Q0D084	ATEG_00650
5		iEKPD-Ast-0123	CADATEAG00008548	Q0CST2	ATEG_03252
6		iEKPD-Ast-0124	CADATEAG00008561	Q0CSL8	ATEG_03316