Ficedula albicollis      CMGC/MAPK


※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase


There are 12 genes.  Reviewed (0 or Unreviewed (12

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Fia-0249
ENSFALG00000007935.1
U3JZS8
MAPK1
2
iEKPD-Fia-0173
ENSFALG00000005585.1
U3JSR1
MAPK10
3
iEKPD-Fia-0294
ENSFALG00000009736.1
U3K560
MAPK11
4
iEKPD-Fia-0293
ENSFALG00000009718.1
U3K537
MAPK12
5
iEKPD-Fia-0114
ENSFALG00000003537.1
U3JLP3
MAPK13
6
iEKPD-Fia-0116
ENSFALG00000003563.1
U3JLS8
MAPK14
7
iEKPD-Fia-0269
ENSFALG00000008664.1
U3K1Y4
MAPK15
8
iEKPD-Fia-0403
ENSFALG00000013641.1
U3KGT1
MAPK4
9
iEKPD-Fia-0351
ENSFALG00000011855.1
U3KBI0
MAPK6
10
iEKPD-Fia-0232
ENSFALG00000007475.1
U3JYE8
MAPK8
11
iEKPD-Fia-0242
ENSFALG00000007690.1
U3JZ19
MAPK9
12
iEKPD-Fia-0154
ENSFALG00000004818.1
U3JQI6
NLK