※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (21) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Mae-0005	MANES_01G017300	A0A2C9WGU0	MANES_01G017300
2		iEKPD-Mae-0017	MANES_01G058000	A0A2C9WKQ2	MANES_01G058000
3		iEKPD-Mae-0049	MANES_01G127600	A0A2C9WMW5	MANES_01G127600
4		iEKPD-Mae-0094	MANES_01G253700	A0A2C9WRL0	MANES_01G253700
5		iEKPD-Mae-0104	MANES_02G018000	A0A2C9WBL6	MANES_02G018000
6		iEKPD-Mae-0111	MANES_02G049600	A0A2C9WAZ4	MANES_02G049600
7		iEKPD-Mae-0128	MANES_02G084400	A0A2C9WC51	MANES_02G084400
8		iEKPD-Mae-0295	MANES_03G186100	A0A2C9W8T7	MANES_03G186100
9		iEKPD-Mae-0312	MANES_04G026700	A0A2C9VZ32	MANES_04G026700
10		iEKPD-Mae-0404	MANES_05G031200	A0A2C9VSY0	MANES_05G031200
11		iEKPD-Mae-0442	MANES_05G132100	A0A2C9VVV7	MANES_05G132100
12		iEKPD-Mae-0449	MANES_05G155300	A0A2C9VZ13	MANES_05G155300
13		iEKPD-Mae-0471	MANES_06G008000	A0A251L1I0	MANES_06G008000
14		iEKPD-Mae-0987	MANES_11G138600	A0A2C9V354	MANES_11G138600
15		iEKPD-Mae-1190	MANES_14G169900	A0A2C9UNG2	MANES_14G169900
16		iEKPD-Mae-1201	MANES_15G021900	A0A2C9UCF8	MANES_15G021900
17		iEKPD-Mae-1232	MANES_15G099900	A0A2C9UEJ5	MANES_15G099900
18		iEKPD-Mae-1243	MANES_15G128200	A0A2C9UGG6	MANES_15G128200
19		iEKPD-Mae-1349	MANES_17G000200	A0A2C9U3T5	MANES_17G000200
20		iEKPD-Mae-1398	MANES_17G077500	A0A2C9U5Y3	MANES_17G077500
21		iEKPD-Mae-1420	MANES_18G020900	A0A251IQ23	MANES_18G020900