※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (17) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Mim-0007	ENSMICG00000000510.3
2		iEKPD-Mim-0008	ENSMICG00000000517.3
3		iEKPD-Mim-0131	ENSMICG00000006997.3
4		iEKPD-Mim-0163	ENSMICG00000008182.3
5		iEKPD-Mim-0164	ENSMICG00000008188.3
6		iEKPD-Mim-0182	ENSMICG00000009154.3
7		iEKPD-Mim-0284	ENSMICG00000014359.3
8		iEKPD-Mim-0291	ENSMICG00000015044.3
9		iEKPD-Mim-0310	ENSMICG00000015900.3
10		iEKPD-Mim-0360	ENSMICG00000027570.2
11		iEKPD-Mim-0361	ENSMICG00000027958.2
12		iEKPD-Mim-0366	ENSMICG00000028966.2
13		iEKPD-Mim-0376	ENSMICG00000030891.2
14		iEKPD-Mim-0389	ENSMICG00000033073.2
15		iEKPD-Mim-0412	ENSMICG00000036229.2
16		iEKPD-Mim-0436	ENSMICG00000042219.1
17		iEKPD-Mim-0442	ENSMICG00000042838.1