※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (16) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Nia-0616	A4A49_41446	A0A1J6JYN3	MMK2_1
2		iEKPD-Nia-0372	A4A49_26742	A0A1J6II62	MPK10
3		iEKPD-Nia-0378	A4A49_26987	A0A1J6I2D7	MPK16
4		iEKPD-Nia-0594	A4A49_39675	A0A1J6JVE5	MPK19_0
5		iEKPD-Nia-0234	A4A49_17644	A0A1J6INA0	MPK19_1
6		iEKPD-Nia-0575	A4A49_37973	A0A1J6KJD9	MPK3_0
7		iEKPD-Nia-0382	A4A49_27214	A0A1J6IKA5	MPK3_1
8		iEKPD-Nia-0184	A4A49_11853	H6T4K4	MPK4
9		iEKPD-Nia-0659	A4A49_59654	A0A1J6KXY8	MPK7
10		iEKPD-Nia-0272	A4A49_20483	A0A1J6ID00	MPK9_0
11		iEKPD-Nia-0453	A4A49_31660	A0A1J6IE15	MPK9_3
12		iEKPD-Nia-0092	A4A49_05349	A0A1J6HX82	NTF3_0
13		iEKPD-Nia-0006	A4A49_00318	A0A1J6IGF0	NTF3_1
14		iEKPD-Nia-g004	A4A49_19919	A0A1J6ICV6	NTF3_2
15		iEKPD-Nia-0113	A4A49_06493	A5H2L0	NTF4_1
16		iEKPD-Nia-0045	A4A49_02839	A0A1J6HRW1	NTF6