Physcomitrella patens      CMGC/MAPK


※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase


There are 18 genes.  Reviewed (2 or Unreviewed (16

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Php-0127
PP1S149_39V6
A9T142
MPK4a
2
iEKPD-Php-0679
PP1S59_325V6
A9S9Q8
MPK4b
3
iEKPD-Php-0154
PP1S15_308V6
4
iEKPD-Php-0285
PP1S20_266V6
5
iEKPD-Php-0290
PP1S211_100V6
6
iEKPD-Php-0338
PP1S230_16V6
7
iEKPD-Php-0361
PP1S246_133V6
8
iEKPD-Php-0366
PP1S248_65V6
9
iEKPD-Php-0452
PP1S30_13V6
10
iEKPD-Php-0776
PP1S88_14V6
11
iEKPD-Php-g007
PP1S20_265V6
12
iEKPD-Php-0426
PP1S29_285V6
A9RUQ3
PHYPADRAFT_105202
13
iEKPD-Php-0755
PP1S80_71V6
A9SHS9
PHYPADRAFT_130039
14
iEKPD-Php-0774
PP1S87_157V6
A9SKC7
PHYPADRAFT_131187
15
iEKPD-Php-0801
PP1S99_26V6
A9SNU1
PHYPADRAFT_132891
16
iEKPD-Php-0559
PP1S39_131V6
A9S0A9
PHYPADRAFT_56569
17
iEKPD-Php-0277
PP1S207_63V6
A9TD42
PHYPA_009927
18
iEKPD-Php-0100
PP1S138_117V6
A9SYS2
PHYPA_015553