※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (19) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Sem-0875	SELMODRAFT_449429	D8R8H3	MPK1
2		iEKPD-Sem-0911	SELMODRAFT_450111	D8QQG3	MPK1-2
3		iEKPD-Sem-0915	SELMODRAFT_450117	D8QN49	MPK16-1
4		iEKPD-Sem-0912	SELMODRAFT_450112	D8RZ17	MPK2-2
5		iEKPD-Sem-0874	SELMODRAFT_449420	D8RZE3	MPK4-2
6		iEKPD-Sem-0913	SELMODRAFT_450114	D8SLN4	MPK9-1
7		iEKPD-Sem-0914	SELMODRAFT_450116	D8RMK2	MPK9-2
8		iEKPD-Sem-0887	SELMODRAFT_449503	D8S7R9	MPK_1
9		iEKPD-Sem-1092	SELMODRAFT_86578	D8R731	MPK_2
10		iEKPD-Sem-0226	SELMODRAFT_131428	D8T437	SELMODRAFT_131428
11		iEKPD-Sem-0480	SELMODRAFT_232896	D8S135	SELMODRAFT_232896
12		iEKPD-Sem-0566	SELMODRAFT_29081	D8SR91	SELMODRAFT_29081
13		iEKPD-Sem-0591	SELMODRAFT_3276	D8QUG7	SELMODRAFT_3276
14		iEKPD-Sem-0598	SELMODRAFT_34645	D8T0C5	SELMODRAFT_34645
15		iEKPD-Sem-0666	SELMODRAFT_4073	D8T301	SELMODRAFT_4073
16		iEKPD-Sem-0691	SELMODRAFT_411235	D8RH02	SELMODRAFT_411235
17		iEKPD-Sem-0730	SELMODRAFT_418401	D8S5L0	SELMODRAFT_418401
18		iEKPD-Sem-0760	SELMODRAFT_423911	D8SN74	SELMODRAFT_423911
19		iEKPD-Sem-1054	SELMODRAFT_82767	D8R0V8	SELMODRAFT_82767