※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (15) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Tag-0377	ENSTGUG00000012787.1	H0ZRC1
2		iEKPD-Tag-0456	ENSTGUG00000015060.1	H0ZXQ6
3		iEKPD-Tag-0457	ENSTGUG00000015065.1	H0ZXT0
4		iEKPD-Tag-0512	ENSTGUG00000016564.1	H1A1W4	LOC100218416
5		iEKPD-Tag-0271	ENSTGUG00000008602.1	H0ZE69	MAPK1
6		iEKPD-Tag-0095	ENSTGUG00000002750.1	H0YX11	MAPK10
7		iEKPD-Tag-0138	ENSTGUG00000004078.1	H0Z0Y9	MAPK11
8		iEKPD-Tag-0137	ENSTGUG00000004046.1	H0Z0V2	MAPK12
9		iEKPD-Tag-0063	ENSTGUG00000001624.1	H0YTR4	MAPK13
10		iEKPD-Tag-0065	ENSTGUG00000001633.1	H0YTS8	MAPK14
11		iEKPD-Tag-0482	ENSTGUG00000015839.1	H0ZZW5	MAPK4
12		iEKPD-Tag-0221	ENSTGUG00000006789.1	H0Z8U6	MAPK6
13		iEKPD-Tag-0255	ENSTGUG00000008103.1	H0ZCT0	MAPK8
14		iEKPD-Tag-0046	ENSTGUG00000001138.1	H0YSC0	MAPK9
15		iEKPD-Tag-0277	ENSTGUG00000008692.1	H0ZEE5	NLK