Aspergillus flavus      CMGC/SRPK


※ SRPK family introduction

    SRPK (serine-arginine (SR) protein kinase) belong to CMGC family. Three members have been identified in human genome, which are known as SRPK1, SRPK2 and SRPK3. SRPKs are characterized by the ability to phosphorylate the serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. More than 100 proteins contain RS domains, indicating that SRPKs are involved in a variety of cellular functions, including regulation and function in mRNA maturation, regulation of chromatin binding to the nuclear envelope, regulation of chromatin reorganization during G2/M phase progression, regulation of cyclin transcription and involved in metabolic signaling (1).

Reference
1. Giannakouros, T., Nikolakaki, E., Mylonis, I. and Georgatsou, E. (2011) Serine-arginine protein kinases: a small protein kinase family with a large cellular presence. FEBS J, 278, 570-586. PMID: 21205200


There are 15 genes.  Reviewed (0 or Unreviewed (15

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Asf-0010
AFLA_008230
B8NXK4
AFLA_008230
2
iEKPD-Asf-0011
AFLA_009240
B8NXV4
AFLA_009240
3
iEKPD-Asf-g004
AFLA_010150
B8NY45
AFLA_010150
4
iEKPD-Asf-0032
AFLA_039070
B8NCK0
AFLA_039070
5
iEKPD-Asf-0034
AFLA_040490
B8NC74
AFLA_040490
6
iEKPD-Asf-0035
AFLA_040840
B8NCA9
AFLA_040840
7
iEKPD-Asf-0066
AFLA_072390
B8MVP2
AFLA_072390
8
iEKPD-Asf-0067
AFLA_073370
B8MVZ0
AFLA_073370
9
iEKPD-Asf-0070
AFLA_074330
B8MW86
AFLA_074330
10
iEKPD-Asf-0086
AFLA_090280
B8NLA1
AFLA_090280
11
iEKPD-Asf-0087
AFLA_090470
B8NLC0
AFLA_090470
12
iEKPD-Asf-0100
AFLA_094860
B8NM54
AFLA_094860
13
iEKPD-Asf-0113
AFLA_106860
B8N892
AFLA_106860
14
iEKPD-Asf-0126
AFLA_123790
B8NME3
AFLA_123790
15
iEKPD-Asf-0146
AFLA_138880
B8NHV2
AFLA_138880