※ SRPK family introduction

    SRPK (serine-arginine (SR) protein kinase) belong to CMGC family. Three members have been identified in human genome, which are known as SRPK1, SRPK2 and SRPK3. SRPKs are characterized by the ability to phosphorylate the serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. More than 100 proteins contain RS domains, indicating that SRPKs are involved in a variety of cellular functions, including regulation and function in mRNA maturation, regulation of chromatin binding to the nuclear envelope, regulation of chromatin reorganization during G2/M phase progression, regulation of cyclin transcription and involved in metabolic signaling (1).

Reference
1. Giannakouros, T., Nikolakaki, E., Mylonis, I. and Georgatsou, E. (2011) Serine-arginine protein kinases: a small protein kinase family with a large cellular presence. FEBS J, 278, 570-586. PMID: 21205200

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Aso-0019	AO090005000005	Q2UTI3	AO090005000005
2		iEKPD-Aso-0048	AO090011000088	Q2U1C3	AO090011000088
3		iEKPD-Aso-0049	AO090011000223	Q2U105	AO090011000223
4		iEKPD-Aso-0050	AO090011000255	Q2U0Y1	AO090011000255
5		iEKPD-Aso-0076	AO090023000160	Q2UI79	AO090023000160
6		iEKPD-Aso-0077	AO090023000262	Q2UHY3	AO090023000262
7		iEKPD-Aso-0114	AO090103000208	Q2TYK5	AO090103000208
8		iEKPD-Aso-0116	AO090103000303	Q2TYC5	AO090103000303
9		iEKPD-Aso-0122	AO090120000030	Q2U6Z6	AO090120000030
10		iEKPD-Aso-0142	AO090138000188	Q2U1L4	AO090138000188