Aspergillus terreus      CMGC/SRPK


※ SRPK family introduction

    SRPK (serine-arginine (SR) protein kinase) belong to CMGC family. Three members have been identified in human genome, which are known as SRPK1, SRPK2 and SRPK3. SRPKs are characterized by the ability to phosphorylate the serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. More than 100 proteins contain RS domains, indicating that SRPKs are involved in a variety of cellular functions, including regulation and function in mRNA maturation, regulation of chromatin binding to the nuclear envelope, regulation of chromatin reorganization during G2/M phase progression, regulation of cyclin transcription and involved in metabolic signaling (1).

Reference
1. Giannakouros, T., Nikolakaki, E., Mylonis, I. and Georgatsou, E. (2011) Serine-arginine protein kinases: a small protein kinase family with a large cellular presence. FEBS J, 278, 570-586. PMID: 21205200


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ast-0086
CADATEAG00005748
Q0D166
ATEG_00318
2
iEKPD-Ast-0097
CADATEAG00006612
Q0D0I1
ATEG_00553
3
iEKPD-Ast-0138
CADATEAG00009618
Q0CNR8
ATEG_04666
4
iEKPD-Ast-0119
CADATEAG00008156
Q0CND7
ATEG_04797
5
iEKPD-Ast-0082
CADATEAG00005351
Q0CMQ5
ATEG_05029
6
iEKPD-Ast-0032
CADATEAG00002319
Q0CJT6
ATEG_06048
7
iEKPD-Ast-0092
CADATEAG00006204
Q0CIR2
ATEG_06422
8
iEKPD-Ast-0008
CADATEAG00000669
Q0CGS1
ATEG_07121
9
iEKPD-Ast-0069
CADATEAG00004607
Q0C8S1
ATEG_09913
10
iEKPD-Ast-0009
CADATEAG00000729
Q0C853
ATEG_10131
11
iEKPD-Ast-0048
CADATEAG00003168
Q0C7J0
ATEG_10344