※ SRPK family introduction

    SRPK (serine-arginine (SR) protein kinase) belong to CMGC family. Three members have been identified in human genome, which are known as SRPK1, SRPK2 and SRPK3. SRPKs are characterized by the ability to phosphorylate the serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. More than 100 proteins contain RS domains, indicating that SRPKs are involved in a variety of cellular functions, including regulation and function in mRNA maturation, regulation of chromatin binding to the nuclear envelope, regulation of chromatin reorganization during G2/M phase progression, regulation of cyclin transcription and involved in metabolic signaling (1).

Reference
1. Giannakouros, T., Nikolakaki, E., Mylonis, I. and Georgatsou, E. (2011) Serine-arginine protein kinases: a small protein kinase family with a large cellular presence. FEBS J, 278, 570-586. PMID: 21205200

  Reviewed (0)  or Unreviewed (6) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Gas-0011	GGTG_00749	J3NHL2	GGTG_00749
2		iEKPD-Gas-0028	GGTG_02732	J3NN74	GGTG_02732
3		iEKPD-Gas-0059	GGTG_04999	J3NUP3	GGTG_04999
4		iEKPD-Gas-0060	GGTG_05014	J3NUQ8	GGTG_05014
5		iEKPD-Gas-0071	GGTG_06061	J3NXQ6	GGTG_06061
6		iEKPD-Gas-0078	GGTG_06611	J3NZB2	GGTG_06611