Macaca mulatta      CMGC/SRPK


※ SRPK family introduction

    SRPK (serine-arginine (SR) protein kinase) belong to CMGC family. Three members have been identified in human genome, which are known as SRPK1, SRPK2 and SRPK3. SRPKs are characterized by the ability to phosphorylate the serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. More than 100 proteins contain RS domains, indicating that SRPKs are involved in a variety of cellular functions, including regulation and function in mRNA maturation, regulation of chromatin binding to the nuclear envelope, regulation of chromatin reorganization during G2/M phase progression, regulation of cyclin transcription and involved in metabolic signaling (1).

Reference
1. Giannakouros, T., Nikolakaki, E., Mylonis, I. and Georgatsou, E. (2011) Serine-arginine protein kinases: a small protein kinase family with a large cellular presence. FEBS J, 278, 570-586. PMID: 21205200


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Mam-0159
ENSMMUG00000009899.3
F6YE11
2
iEKPD-Mam-0451
ENSMMUG00000041828.1
A0A1D5R8F8
3
iEKPD-Mam-0317
ENSMMUG00000018557.3
A0A1D5RAZ4
SRPK1
4
iEKPD-Mam-0407
ENSMMUG00000022732.3
A0A1D5QEA9
SRPK2
5
iEKPD-Mam-0046
ENSMMUG00000003372.3
A0A1D5QZE4
SRPK3