Medicago truncatula      CMGC/SRPK


※ SRPK family introduction

    SRPK (serine-arginine (SR) protein kinase) belong to CMGC family. Three members have been identified in human genome, which are known as SRPK1, SRPK2 and SRPK3. SRPKs are characterized by the ability to phosphorylate the serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. More than 100 proteins contain RS domains, indicating that SRPKs are involved in a variety of cellular functions, including regulation and function in mRNA maturation, regulation of chromatin binding to the nuclear envelope, regulation of chromatin reorganization during G2/M phase progression, regulation of cyclin transcription and involved in metabolic signaling (1).

Reference
1. Giannakouros, T., Nikolakaki, E., Mylonis, I. and Georgatsou, E. (2011) Serine-arginine protein kinases: a small protein kinase family with a large cellular presence. FEBS J, 278, 570-586. PMID: 21205200


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Met-0936
MTR_5g024270
G7K189
11410596
2
iEKPD-Met-0185
MTR_1g061690
G7I9C7
11434131
3
iEKPD-Met-1516
MTR_8g073250
G7L8Q0
11445329
4
iEKPD-Met-0434
MTR_2g084555
A0A072VA73
25487481
5
iEKPD-Met-0723
MTR_4g056390
A0A072UJU0
25492350