Neosartorya fischeri      CMGC/SRPK


※ SRPK family introduction

    SRPK (serine-arginine (SR) protein kinase) belong to CMGC family. Three members have been identified in human genome, which are known as SRPK1, SRPK2 and SRPK3. SRPKs are characterized by the ability to phosphorylate the serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. More than 100 proteins contain RS domains, indicating that SRPKs are involved in a variety of cellular functions, including regulation and function in mRNA maturation, regulation of chromatin binding to the nuclear envelope, regulation of chromatin reorganization during G2/M phase progression, regulation of cyclin transcription and involved in metabolic signaling (1).

Reference
1. Giannakouros, T., Nikolakaki, E., Mylonis, I. and Georgatsou, E. (2011) Serine-arginine protein kinases: a small protein kinase family with a large cellular presence. FEBS J, 278, 570-586. PMID: 21205200


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Nef-0002
CADNFIAG00000129
A1DJD6
NFIA_001740
2
iEKPD-Nef-0004
CADNFIAG00000581
A1DJN3
NFIA_002740
3
iEKPD-Nef-0025
CADNFIAG00002669
A1D9W8
NFIA_030320
4
iEKPD-Nef-0050
CADNFIAG00004093
A1CVG9
NFIA_045660
5
iEKPD-Nef-0065
CADNFIAG00005360
A1DNN5
NFIA_057560
6
iEKPD-Nef-0076
CADNFIAG00005899
A1D6X4
NFIA_066320
7
iEKPD-Nef-0097
CADNFIAG00007448
A1DDF8
NFIA_073300