Physcomitrella patens      CMGC/SRPK


※ SRPK family introduction

    SRPK (serine-arginine (SR) protein kinase) belong to CMGC family. Three members have been identified in human genome, which are known as SRPK1, SRPK2 and SRPK3. SRPKs are characterized by the ability to phosphorylate the serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. More than 100 proteins contain RS domains, indicating that SRPKs are involved in a variety of cellular functions, including regulation and function in mRNA maturation, regulation of chromatin binding to the nuclear envelope, regulation of chromatin reorganization during G2/M phase progression, regulation of cyclin transcription and involved in metabolic signaling (1).

Reference
1. Giannakouros, T., Nikolakaki, E., Mylonis, I. and Georgatsou, E. (2011) Serine-arginine protein kinases: a small protein kinase family with a large cellular presence. FEBS J, 278, 570-586. PMID: 21205200


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Php-0293
PP1S212_89V6
A9TE73
PHYPADRAFT_144157
2
iEKPD-Php-0427
PP1S29_327V6
A9RUT0
PHYPADRAFT_22378
3
iEKPD-Php-0548
PP1S38_279V6
A9RZY6
PHYPADRAFT_22627
4
iEKPD-Php-0363
PP1S248_102V6
A9TK52
PHYPADRAFT_2613