※ SRPK family introduction

    SRPK (serine-arginine (SR) protein kinase) belong to CMGC family. Three members have been identified in human genome, which are known as SRPK1, SRPK2 and SRPK3. SRPKs are characterized by the ability to phosphorylate the serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. More than 100 proteins contain RS domains, indicating that SRPKs are involved in a variety of cellular functions, including regulation and function in mRNA maturation, regulation of chromatin binding to the nuclear envelope, regulation of chromatin reorganization during G2/M phase progression, regulation of cyclin transcription and involved in metabolic signaling (1).

Reference
1. Giannakouros, T., Nikolakaki, E., Mylonis, I. and Georgatsou, E. (2011) Serine-arginine protein kinases: a small protein kinase family with a large cellular presence. FEBS J, 278, 570-586. PMID: 21205200

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Sem-0076	SELMODRAFT_110202	D8S728	SELMODRAFT_110202
2		iEKPD-Sem-0441	SELMODRAFT_184470	D8T118	SELMODRAFT_184470
3		iEKPD-Sem-g044	SELMODRAFT_420523	D8SC97	SELMODRAFT_420523
4		iEKPD-Sem-0816	SELMODRAFT_43162	D8SYV5	SELMODRAFT_43162
5		iEKPD-Sem-0939	SELMODRAFT_53092	D8SC96	SELMODRAFT_53092