Helianthus annuus      Other/IRE


※ IRE family introduction

    IRE family kinases are endoribonuclease that functions in the interferon (IFN) antiviral response. In INF treated and virus infected cells, family member RNASEL probably mediates its antiviral effects through a combination of direct cleavage of single-stranded viral RNAs, inhibition of protein synthesis through the degradation of rRNA, induction of apoptosis, and induction of other antiviral genes. RNASEL mediated apoptosis is the result of a JNK-dependent stress-response pathway leading to cytochrome c release from mitochondria and caspase-dependent apoptosis. Therefore, activation of RNASEL could lead to elimination of virus infected cells under some circumstances. RNASEL might also play a central role in the regulation of mRNA. turnover (1).

Reference
1. UniProt Annotation: RN5A_HUMAN


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Hea-1873
HannXRQ_Chr14g0427841
A0A251SDB4
HannXRQ_Chr14g0427841
2
iEKPD-Hea-2189
HannXRQ_Chr15g0482881
A0A251S991
HannXRQ_Chr15g0482881
3
iEKPD-Hea-2190
HannXRQ_Chr15g0482891
A0A251SDB5
HannXRQ_Chr15g0482891
4
iEKPD-Hea-2384
HannXRQ_Chr16g0531931
A0A251S3Q9
HannXRQ_Chr16g0531931