Danio rerio      Other/NKF1


※ NKF1 family introduction

    NKF1 kinases belong to "Other" group. This family was first defined in human kinome paper as New Kinase Family 1. NKF1 kinases are present in most animals and threes members have been classified in human genome, SBK1, SgK069 and SgK110, for their highly similar protein kinase catalytic domain. NKF1 kinases are also known as SH3-Binding domain kinase for their ability to interact with Fas SH3 domains. NKF1 kinases have been identified as a survival factor for ovarian carcinoma cell line and to be dysregulatd in cancers. Xenopus homolog SBK1 have been found expressed only in blastula and gastrula stages of development and played an important role in control of microtubules (1).

Reference
1. Kinase Family NKF1: http://kinase.com/wiki/index.php/Kinase_Family_NKF1


There are 6 genes.  Reviewed (1 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Dar-0832
ENSDARG00000099069.1
Q90ZY4
sbk1
2
iEKPD-Dar-0376
ENSDARG00000057687.4
A8WFZ8
sbk3
3
iEKPD-Dar-0159
ENSDARG00000020455.7
A0A0R4IDR3
si:ch211-171h4.3
4
iEKPD-Dar-0356
ENSDARG00000056294.4
E7F802
si:ch211-183d21.3
5
iEKPD-Dar-0396
ENSDARG00000058944.5
F1QWH2
si:dkey-8e10.3
6
iEKPD-Dar-0218
ENSDARG00000031618.6
E7F705
unm_sa1261