Oreochromis niloticus      Other/NKF1


※ NKF1 family introduction

    NKF1 kinases belong to "Other" group. This family was first defined in human kinome paper as New Kinase Family 1. NKF1 kinases are present in most animals and threes members have been classified in human genome, SBK1, SgK069 and SgK110, for their highly similar protein kinase catalytic domain. NKF1 kinases are also known as SH3-Binding domain kinase for their ability to interact with Fas SH3 domains. NKF1 kinases have been identified as a survival factor for ovarian carcinoma cell line and to be dysregulatd in cancers. Xenopus homolog SBK1 have been found expressed only in blastula and gastrula stages of development and played an important role in control of microtubules (1).

Reference
1. Kinase Family NKF1: http://kinase.com/wiki/index.php/Kinase_Family_NKF1


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Orn-0192
ENSONIG00000007062.1
I3JJ70
2
iEKPD-Orn-0392
ENSONIG00000012818.1
I3K4T8
3
iEKPD-Orn-0253
ENSONIG00000009090.1
I3JRD9
LOC100690206
4
iEKPD-Orn-0590
ENSONIG00000020004.1
I3KVP3
LOC100695188
5
iEKPD-Orn-0276
ENSONIG00000009691.1
I3JTH7
LOC100709498
6
iEKPD-Orn-0578
ENSONIG00000019578.1
I3KU50
LOC100712334