Xenopus tropicalis      Other/NKF1


※ NKF1 family introduction

    NKF1 kinases belong to "Other" group. This family was first defined in human kinome paper as New Kinase Family 1. NKF1 kinases are present in most animals and threes members have been classified in human genome, SBK1, SgK069 and SgK110, for their highly similar protein kinase catalytic domain. NKF1 kinases are also known as SH3-Binding domain kinase for their ability to interact with Fas SH3 domains. NKF1 kinases have been identified as a survival factor for ovarian carcinoma cell line and to be dysregulatd in cancers. Xenopus homolog SBK1 have been found expressed only in blastula and gastrula stages of development and played an important role in control of microtubules (1).

Reference
1. Kinase Family NKF1: http://kinase.com/wiki/index.php/Kinase_Family_NKF1


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Xet-0051
ENSXETG00000002351.1
F6ZIA8
2
iEKPD-Xet-0211
ENSXETG00000010325.3
F6TNM0
3
iEKPD-Xet-0343
ENSXETG00000016923.3
A9UM37
LOC100135243
4
iEKPD-Xet-0252
ENSXETG00000012254.3
F6VK53
LOC100495913
5
iEKPD-Xet-0167
ENSXETG00000008802.3
F6WD10
sbk1
6
iEKPD-Xet-0367
ENSXETG00000018197.2
F7AWP8
sbk1
7
iEKPD-Xet-0390
ENSXETG00000019143.3
F7C670
sbk2