Aegilops tauschii      Other/SCY


※ SCY family introduction

    SCY1 family is composed of three members in human genome (1). SCYL1 is involved in regulating COPI-mediated retrograde traffic. Isoform 6 acts as transcriptional activator. It binds to three different types of GC-rich DNA binding sites (box-A, -B and -C) in the beta-polymerase promoter region. It also binds to the TERT promoter region (2). SCYL2 is component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles and may regulate clathrin-dependent trafficking between the TGN and/or the endosomal system (3).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. UniProt Annotation:   NTKL_HUMAN;
3. UniProt Annotation:   SCYL2_HUMAN;


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Aet-0186
F775_04638
M8BIE6
F775_04638
2
iEKPD-Aet-0382
F775_09102
M8C6P5
F775_09102
3
iEKPD-Aet-1271
F775_23425
N1QSJ2
F775_23425
4
iEKPD-Aet-1325
F775_24779
N1QSX1
F775_24779
5
iEKPD-Aet-1460
F775_26501
M8BDX4
F775_26501
6
iEKPD-Aet-1596
F775_31253
M8CGP7
F775_31253
7
iEKPD-Aet-1676
F775_43302
M8BVC6
F775_43302