※ SCY family introduction

    SCY1 family is composed of three members in human genome (1). SCYL1 is involved in regulating COPI-mediated retrograde traffic. Isoform 6 acts as transcriptional activator. It binds to three different types of GC-rich DNA binding sites (box-A, -B and -C) in the beta-polymerase promoter region. It also binds to the TERT promoter region (2). SCYL2 is component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles and may regulate clathrin-dependent trafficking between the TGN and/or the endosomal system (3).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. UniProt Annotation:   NTKL_HUMAN;
3. UniProt Annotation:   SCYL2_HUMAN;

  Reviewed (0)  or Unreviewed (8) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Arl-0339	fgenesh2_kg.1__2486__AT1G22870.1	D7KMK3	ARALYDRAFT_472532
2		iEKPD-Arl-g006	Al_scaffold_0007_1084	D7MC73	ARALYDRAFT_657029
3		iEKPD-Arl-0086	Al_scaffold_0005_2693	D7LVW6	ARALYDRAFT_666658
4		iEKPD-Arl-0881	scaffold_202063.1	D7KYV4	ARALYDRAFT_894989
5		iEKPD-Arl-1625	scaffold_301783.1	D7L418	ARALYDRAFT_897813
6		iEKPD-Arl-0944	scaffold_402867.1	D7LFT7	ARALYDRAFT_903366
7		iEKPD-Arl-g003	scaffold_501695.1	D7LRD5	ARALYDRAFT_905991
8		iEKPD-Arl-1627	scaffold_603489.1	D7LYW8	ARALYDRAFT_911432