Brachypodium distachyon      Other/SCY


※ SCY family introduction

    SCY1 family is composed of three members in human genome (1). SCYL1 is involved in regulating COPI-mediated retrograde traffic. Isoform 6 acts as transcriptional activator. It binds to three different types of GC-rich DNA binding sites (box-A, -B and -C) in the beta-polymerase promoter region. It also binds to the TERT promoter region (2). SCYL2 is component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles and may regulate clathrin-dependent trafficking between the TGN and/or the endosomal system (3).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. UniProt Annotation:   NTKL_HUMAN;
3. UniProt Annotation:   SCYL2_HUMAN;


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Brd-0360
BRADI1G78820
I1HB05
2
iEKPD-Brd-0983
BRADI4G24020
I1IN10
3
iEKPD-Brd-g023
BRADI1G00390
I1GKF6
4
iEKPD-Brd-g003
BRADI3G16837
I1I1I9
5
iEKPD-Brd-g001
BRADI1G48020
I1H0K9
BRADI_1g48020v3
6
iEKPD-Brd-0543
BRADI2G43580
I1HPE7
LOC100827476
7
iEKPD-Brd-1521
BRADI2G48657
I1HR44
LOC100833269
8
iEKPD-Brd-0602
BRADI2G53460
I1HSV4
LOC100839682