※ SCY family introduction

    SCY1 family is composed of three members in human genome (1). SCYL1 is involved in regulating COPI-mediated retrograde traffic. Isoform 6 acts as transcriptional activator. It binds to three different types of GC-rich DNA binding sites (box-A, -B and -C) in the beta-polymerase promoter region. It also binds to the TERT promoter region (2). SCYL2 is component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles and may regulate clathrin-dependent trafficking between the TGN and/or the endosomal system (3).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. UniProt Annotation:   NTKL_HUMAN;
3. UniProt Annotation:   SCYL2_HUMAN;

  Reviewed (0)  or Unreviewed (11) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Bro-2655	Bo4g009360	A0A0D3BNU7
2		iEKPD-Bro-1037	Bo5g038950	A0A0D3CCJ2
3		iEKPD-Bro-1107	Bo5g137420	A0A0D3CLF6
4		iEKPD-Bro-g056	Bo2g168310	A0A0D3AZ02
5		iEKPD-Bro-g021	Bo4g061370	A0A0D3BTT3
6		iEKPD-Bro-1270	Bo6g112990	A0A0D3CZV1	106300326
7		iEKPD-Bro-2663	Bo9g091030	A0A0D3E951	106318333
8		iEKPD-Bro-0353	Bo2g072880	A0A0D3APU6	106327295
9		iEKPD-Bro-0536	Bo3g035120	A0A0D3B637	106335035
10		iEKPD-Bro-2652	Bo3g039180	A0A0D3B6Z4	106335477
11		iEKPD-Bro-0947	Bo4g190370	A0A0D3C5H2	106342494