※ SCY family introduction

    SCY1 family is composed of three members in human genome (1). SCYL1 is involved in regulating COPI-mediated retrograde traffic. Isoform 6 acts as transcriptional activator. It binds to three different types of GC-rich DNA binding sites (box-A, -B and -C) in the beta-polymerase promoter region. It also binds to the TERT promoter region (2). SCYL2 is component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles and may regulate clathrin-dependent trafficking between the TGN and/or the endosomal system (3).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. UniProt Annotation:   NTKL_HUMAN;
3. UniProt Annotation:   SCYL2_HUMAN;

  Reviewed (0)  or Unreviewed (11) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Glm-0915	GLYMA_08G287900
2		iEKPD-Glm-3350	GLYMA_12G224600
3		iEKPD-Glm-2124	GLYMA_18G240600	I1N3X7	100782748
4		iEKPD-Glm-3339	GLYMA_06G242100	I1KDV9	100784064
5		iEKPD-Glm-0947	GLYMA_09G002400	I1KZR6	100788400
6		iEKPD-Glm-1053	GLYMA_09G252000	I1L6C2	100789813
7		iEKPD-Glm-2354	GLYMA_20G219600	I1NIJ6	100792884
8		iEKPD-Glm-1418	GLYMA_12G241900	I1LVI0	100796211
9		iEKPD-Glm-3114	GLYMA_13G276700	K7M2B8	100809718
10		iEKPD-Glm-3349	GLYMA_12G155700	I1LT55	100813635
11		iEKPD-Glm-g005	GLYMA_10G170400	K7LJX3	GLYMA_10G170400