Medicago truncatula      Other/SCY


※ SCY family introduction

    SCY1 family is composed of three members in human genome (1). SCYL1 is involved in regulating COPI-mediated retrograde traffic. Isoform 6 acts as transcriptional activator. It binds to three different types of GC-rich DNA binding sites (box-A, -B and -C) in the beta-polymerase promoter region. It also binds to the TERT promoter region (2). SCYL2 is component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles and may regulate clathrin-dependent trafficking between the TGN and/or the endosomal system (3).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. UniProt Annotation:   NTKL_HUMAN;
3. UniProt Annotation:   SCYL2_HUMAN;


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Met-2210
MTR_2g085210
G7IRA7
11411033
2
iEKPD-Met-g027
MTR_2g045660
G7IST8
11418343
3
iEKPD-Met-0706
MTR_4g030910
G7JKS9
11431787
4
iEKPD-Met-1513
MTR_8g071950
G7L750
11446509
5
iEKPD-Met-0201
MTR_1g078330
A0A072VMW2
25484601
6
iEKPD-Met-g022
MTR_6g043270
A0A072UJN2
25496292
7
iEKPD-Met-1155
MTR_6g086565
A0A072UBV6
25496905