※ SCY family introduction

    SCY1 family is composed of three members in human genome (1). SCYL1 is involved in regulating COPI-mediated retrograde traffic. Isoform 6 acts as transcriptional activator. It binds to three different types of GC-rich DNA binding sites (box-A, -B and -C) in the beta-polymerase promoter region. It also binds to the TERT promoter region (2). SCYL2 is component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles and may regulate clathrin-dependent trafficking between the TGN and/or the endosomal system (3).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. UniProt Annotation:   NTKL_HUMAN;
3. UniProt Annotation:   SCYL2_HUMAN;

  Reviewed (0)  or Unreviewed (14) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Tra-0099	TRIAE_CS42_1AL_TGACv1_002522_AA0042790	A0A1D5RXX7
2		iEKPD-Tra-1062	TRIAE_CS42_2BS_TGACv1_146762_AA0472280	A0A1D5UB25
3		iEKPD-Tra-1490	TRIAE_CS42_3AL_TGACv1_194598_AA0636510	A0A1D5V8R9
4		iEKPD-Tra-5715	TRIAE_CS42_3AL_TGACv1_196100_AA0657300	A0A1D5VDD5
5		iEKPD-Tra-1746	TRIAE_CS42_3B_TGACv1_221321_AA0737290	A0A1D5VTC2
6		iEKPD-Tra-5731	TRIAE_CS42_3B_TGACv1_224806_AA0801770	A0A1D5W6J1
7		iEKPD-Tra-5710	TRIAE_CS42_3DL_TGACv1_249089_AA0837260	A0A1D6RS04
8		iEKPD-Tra-1995	TRIAE_CS42_3DL_TGACv1_249344_AA0845940	A0A1D5WEB5
9		iEKPD-Tra-2039	TRIAE_CS42_3DL_TGACv1_250166_AA0863480	A0A1D5WHW3
10		iEKPD-Tra-3119	TRIAE_CS42_5BS_TGACv1_423244_AA1372090	A0A1D5ZEJ6
11		iEKPD-Tra-3653	TRIAE_CS42_6BL_TGACv1_501299_AA1615780	A0A1D6AS01
12		iEKPD-Tra-6214	TRIAE_CS42_7AL_TGACv1_556544_AA1765070	A0A1D6BJQ4
13		iEKPD-Tra-g027	TRIAE_CS42_2AL_TGACv1_096559_AA0319840	W5AW31
14		iEKPD-Tra-g030	TRIAE_CS42_7DL_TGACv1_604502_AA1998710	A0A1D6CT25