※ PP2C family introduction

    Metal-dependent protein phosphatases (PPM) include protein phosphatases which dependent on manganese/magnesium ions (Mn²⁺/Mg²⁺). PPM group contains a high conserved catalytic domain instead of catalytic subunit and different regulatory domains determining the substrate recognition and function diversity. Like PPP group, metal ions play an important role in dephosphorylation reaction (1). PP2C contains 19 members in human genome, including PP2C like phosphatases. What's more, PP2C is one of the largest type of protein phosphatases in plants with at least 76 members in Arabidopsis thaliana. PP2C family members are involved in varieties of cellular processes including cell cycle, splicing, cellular stress signaling and some members function as tumor suppressor (2).

Reference
1. Shi, Y. (2009) Serine/threonine phosphatases: mechanism through structure. Cell, 139, 468-484. PMID: 19879837
2. Lammers, T. and Lavi, S. (2007) Role of type 2C protein phosphatases in growth regulation and in cellular stress signaling. Crit Rev Biochem Mol Biol, 42, 437-461. PMID: 18066953

  Reviewed (0)  or Unreviewed (106) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Mae-1529	MANES_01G007900	A0A2C9WIY4	MANES_01G007900
2		iEKPD-Mae-1530	MANES_01G040500	A0A2C9WHR1	MANES_01G040500
3		iEKPD-Mae-1533	MANES_01G150400	A0A2C9WL08	MANES_01G150400
4		iEKPD-Mae-1534	MANES_01G156200	A0A2C9WNG2	MANES_01G156200
5		iEKPD-Mae-1536	MANES_01G168600	A0A2C9WNU2	MANES_01G168600
6		iEKPD-Mae-1538	MANES_01G204300	A0A2C9WMH9	MANES_01G204300
7		iEKPD-Mae-1540	MANES_01G232600	A0A2C9WPR0	MANES_01G232600
8		iEKPD-Mae-1541	MANES_01G236400	A0A2C9WQ06	MANES_01G236400
9		iEKPD-Mae-1542	MANES_02G010500	A0A2C9WBG2	MANES_02G010500
10		iEKPD-Mae-1548	MANES_02G109800	A0A2C9WCV7	MANES_02G109800
11		iEKPD-Mae-1549	MANES_02G115000	A0A2C9WD25	MANES_02G115000
12		iEKPD-Mae-1552	MANES_02G128000	A0A2C9WDB8	MANES_02G128000
13		iEKPD-Mae-1553	MANES_02G152100	A0A2C9WE45	MANES_02G152100
14		iEKPD-Mae-1554	MANES_02G152200	A0A2C9WGS1	MANES_02G152200
15		iEKPD-Mae-1555	MANES_02G172800	A0A2C9WEV5	MANES_02G172800
16		iEKPD-Mae-1557	MANES_03G006100	A0A2C9W3G8	MANES_03G006100
17		iEKPD-Mae-1558	MANES_03G007900	A0A2C9W5L7	MANES_03G007900
18		iEKPD-Mae-1559	MANES_03G018800	A0A2C9W3W5	MANES_03G018800
19		iEKPD-Mae-1560	MANES_03G036900	A0A2C9W5R3	MANES_03G036900
20		iEKPD-Mae-1561	MANES_03G050800	A0A2C9W4M7	MANES_03G050800
21		iEKPD-Mae-1563	MANES_03G106800	A0A2C9W7U4	MANES_03G106800
22		iEKPD-Mae-2096	MANES_03G181800	A0A2C9W8N8	MANES_03G181800
23		iEKPD-Mae-1567	MANES_03G187800	A0A2C9W8V6	MANES_03G187800
24		iEKPD-Mae-1568	MANES_03G199700	A0A251LCP0	MANES_03G199700
25		iEKPD-Mae-1569	MANES_03G205700	A0A2C9W978	MANES_03G205700
26		iEKPD-Mae-1570	MANES_03G209200	A0A2C9WBQ3	MANES_03G209200
27		iEKPD-Mae-1572	MANES_04G034600	A0A2C9W0J6	MANES_04G034600
28		iEKPD-Mae-1574	MANES_04G071500	A0A2C9W087	MANES_04G071500
29		iEKPD-Mae-1575	MANES_04G142100	A0A251L4A5	MANES_04G142100
30		iEKPD-Mae-1577	MANES_05G006800	A0A251KRD3	MANES_05G006800
31		iEKPD-Mae-1578	MANES_05G011300	A0A2C9VUE9	MANES_05G011300
32		iEKPD-Mae-2084	MANES_05G081600	A0A251KUC5	MANES_05G081600
33		iEKPD-Mae-1582	MANES_05G162400	A0A2C9VWS3	MANES_05G162400
34		iEKPD-Mae-1583	MANES_05G172200	A0A2C9VX32	MANES_05G172200
35		iEKPD-Mae-1585	MANES_06G041800	A0A2C9VMX8	MANES_06G041800
36		iEKPD-Mae-1586	MANES_06G065700	A0A251KM04	MANES_06G065700
37		iEKPD-Mae-1589	MANES_06G139900	A0A2C9VT37	MANES_06G139900
38		iEKPD-Mae-1590	MANES_06G158500	A0A2C9VTC9	MANES_06G158500
39		iEKPD-Mae-1591	MANES_06G158800	A0A2C9VRB7	MANES_06G158800
40		iEKPD-Mae-1593	MANES_07G063300	A0A2C9VKL6	MANES_07G063300
41		iEKPD-Mae-1595	MANES_07G105800	A0A2C9VK84	MANES_07G105800
42		iEKPD-Mae-1597	MANES_07G119400	A0A2C9VM50	MANES_07G119400
43		iEKPD-Mae-1600	MANES_07G131300	A0A2C9VMG7	MANES_07G131300
44		iEKPD-Mae-1601	MANES_08G000900	A0A2C9VDW9	MANES_08G000900
45		iEKPD-Mae-1604	MANES_08G044400	A0A2C9VDD2	MANES_08G044400
46		iEKPD-Mae-2085	MANES_08G063700	A0A2C9VDX2	MANES_08G063700
47		iEKPD-Mae-1605	MANES_08G078900	A0A2C9VGB7	MANES_08G078900
48		iEKPD-Mae-1607	MANES_08G097500	A0A2C9VF03	MANES_08G097500
49		iEKPD-Mae-1608	MANES_08G114000	A0A251KDM5	MANES_08G114000
50		iEKPD-Mae-1609	MANES_08G114600	A0A2C9VFG5	MANES_08G114600
51		iEKPD-Mae-1614	MANES_09G035500	A0A2C9V985	MANES_09G035500
52		iEKPD-Mae-1616	MANES_09G071400	A0A2C9V8I3	MANES_09G071400
53		iEKPD-Mae-1617	MANES_09G095500	A0A2C9VB15	MANES_09G095500
54		iEKPD-Mae-1620	MANES_09G112400	A0A2C9V9V8	MANES_09G112400
55		iEKPD-Mae-1624	MANES_09G174000	A0A251K921	MANES_09G174000
56		iEKPD-Mae-1625	MANES_09G174400	A0A2C9VCX2	MANES_09G174400
57		iEKPD-Mae-1627	MANES_10G010600	A0A2C9V3G5	MANES_10G010600
58		iEKPD-Mae-1630	MANES_10G026400	A0A2C9V3X5	MANES_10G026400
59		iEKPD-Mae-1632	MANES_10G040000	A0A2C9V336	MANES_10G040000
60		iEKPD-Mae-1635	MANES_10G074700	A0A2C9V691	MANES_10G074700
61		iEKPD-Mae-1638	MANES_11G023300	A0A251JRD5	MANES_11G023300
62		iEKPD-Mae-1639	MANES_11G068300	A0A2C9UZ26	MANES_11G068300
63		iEKPD-Mae-1640	MANES_11G068400	A0A2C9V127	MANES_11G068400
64		iEKPD-Mae-1641	MANES_11G097300	A0A2C9V011	MANES_11G097300
65		iEKPD-Mae-1643	MANES_11G130900	A0A2C9V0Y3	MANES_11G130900
66		iEKPD-Mae-1646	MANES_12G005000	A0A251JJY4	MANES_12G005000
67		iEKPD-Mae-1649	MANES_12G021700	A0A2C9UUA3	MANES_12G021700
68		iEKPD-Mae-1652	MANES_12G112500	A0A2C9UVP3	MANES_12G112500
69		iEKPD-Mae-1653	MANES_13G005000	A0A2C9UNX9	MANES_13G005000
70		iEKPD-Mae-1654	MANES_13G022700	A0A2C9UMX3	MANES_13G022700
71		iEKPD-Mae-1656	MANES_13G068900	A0A251JHB7	MANES_13G068900
72		iEKPD-Mae-1658	MANES_13G114100	A0A2C9UR49	MANES_13G114100
73		iEKPD-Mae-1659	MANES_13G143900	A0A2C9URS8	MANES_13G143900
74		iEKPD-Mae-1660	MANES_13G149200	A0A251JJN0	MANES_13G149200
75		iEKPD-Mae-1661	MANES_14G017800	A0A251J897	MANES_14G017800
76		iEKPD-Mae-1663	MANES_14G105600	A0A2C9UMF4	MANES_14G105600
77		iEKPD-Mae-1664	MANES_14G124300	A0A2C9UL67	MANES_14G124300
78		iEKPD-Mae-1665	MANES_14G137700	A0A2C9ULM4	MANES_14G137700
79		iEKPD-Mae-1666	MANES_14G167000	A0A2C9UMH4	MANES_14G167000
80		iEKPD-Mae-1667	MANES_15G000700	A0A2C9UBT4	MANES_15G000700
81		iEKPD-Mae-1668	MANES_15G009500	A0A2C9UCW2	MANES_15G009500
82		iEKPD-Mae-1669	MANES_15G012600	A0A2C9UCZ9	MANES_15G012600
83		iEKPD-Mae-1670	MANES_15G020300	A0A2C9UC05	MANES_15G020300
84		iEKPD-Mae-2100	MANES_15G025800	A0A2C9UCB5	MANES_15G025800
85		iEKPD-Mae-1674	MANES_15G042300	A0A2C9UD30	MANES_15G042300
86		iEKPD-Mae-1676	MANES_15G088600	A0A2C9UFB1	MANES_15G088600
87		iEKPD-Mae-1679	MANES_15G169600	A0A2C9UGR4	MANES_15G169600
88		iEKPD-Mae-1681	MANES_15G188700	A0A2C9UIF1	MANES_15G188700
89		iEKPD-Mae-1684	MANES_16G078000	A0A2C9UAP7	MANES_16G078000
90		iEKPD-Mae-1685	MANES_16G082900	A0A251IZA8	MANES_16G082900
91		iEKPD-Mae-1686	MANES_16G099200	A0A2C9UA61	MANES_16G099200
92		iEKPD-Mae-1689	MANES_16G109500	A0A2C9UBT1	MANES_16G109500
93		iEKPD-Mae-1690	MANES_16G130500	A0A251J1J6	MANES_16G130500
94		iEKPD-Mae-1691	MANES_16G133100	A0A2C9UBM5	MANES_16G133100
95		iEKPD-Mae-1692	MANES_17G013600	A0A251ITU0	MANES_17G013600
96		iEKPD-Mae-1697	MANES_18G003500	A0A2C9U0R7	MANES_18G003500
97		iEKPD-Mae-1698	MANES_18G028900	A0A2C9U0X9	MANES_18G028900
98		iEKPD-Mae-1699	MANES_18G035500	A0A2C9U0A4	MANES_18G035500
99		iEKPD-Mae-1700	MANES_18G067100	A0A2C9U1W8	MANES_18G067100
100		iEKPD-Mae-1701	MANES_18G067200	A0A2C9U103	MANES_18G067200
101		iEKPD-Mae-1703	MANES_18G116200	A0A2C9U3H0	MANES_18G116200
102		iEKPD-Mae-1705	MANES_18G136400	A0A2C9U336	MANES_18G136400
103		iEKPD-Mae-1706	MANES_18G142800	A0A2C9U479	MANES_18G142800
104		iEKPD-Mae-1707	MANES_18G143700	A0A2C9U3J5	MANES_18G143700
105		iEKPD-Mae-1708	MANES_S025600	A0A199UCH7	MANES_S025600
106		iEKPD-Mae-1709	MANES_S076400	A0A199U9Z6	MANES_S076400