※ PP2C family introduction

    Metal-dependent protein phosphatases (PPM) include protein phosphatases which dependent on manganese/magnesium ions (Mn²⁺/Mg²⁺). PPM group contains a high conserved catalytic domain instead of catalytic subunit and different regulatory domains determining the substrate recognition and function diversity. Like PPP group, metal ions play an important role in dephosphorylation reaction (1). PP2C contains 19 members in human genome, including PP2C like phosphatases. What's more, PP2C is one of the largest type of protein phosphatases in plants with at least 76 members in Arabidopsis thaliana. PP2C family members are involved in varieties of cellular processes including cell cycle, splicing, cellular stress signaling and some members function as tumor suppressor (2).

Reference
1. Shi, Y. (2009) Serine/threonine phosphatases: mechanism through structure. Cell, 139, 468-484. PMID: 19879837
2. Lammers, T. and Lavi, S. (2007) Role of type 2C protein phosphatases in growth regulation and in cellular stress signaling. Crit Rev Biochem Mol Biol, 42, 437-461. PMID: 18066953

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No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Sei-1461	Si017422m.g	K3YT27	LOC101752467
2		iEKPD-Sei-1421	Si030198m.g	K3ZUB7	LOC101753735
3		iEKPD-Sei-1433	Si010770m.g	K3Y978	LOC101754812
4		iEKPD-Sei-1410	Si022243m.g	K3Z6S4	LOC101754855
5		iEKPD-Sei-1454	Si006767m.g	K3XXV9	LOC101756615
6		iEKPD-Sei-1418	Si017582m.g	K3YTI7	LOC101757462
7		iEKPD-Sei-1452	Si036005m.g	K4AAU8	LOC101757840
8		iEKPD-Sei-1837	Si000606m.g	K3XFD7	LOC101758134
9		iEKPD-Sei-1437	Si006835m.g	K3XY27	LOC101758516
10		iEKPD-Sei-1480	Si013567m.g	K3YH49	LOC101758838
11		iEKPD-Sei-1442	Si010771m.g	K3Y979	LOC101758856
12		iEKPD-Sei-1427	Si024914m.g	K3ZEC1	LOC101759288
13		iEKPD-Sei-1450	Si017649m.g	K3YTQ3	LOC101759514
14		iEKPD-Sei-1482	Si039990m.g	K4AM55	LOC101760545
15		iEKPD-Sei-1419	Si022134m.g	K3Z6G5	LOC101760787
16		iEKPD-Sei-1500	Si001244m.g	K3XH73	LOC101761383
17		iEKPD-Sei-1860	Si029313m.g	K3ZRT3	LOC101761811
18		iEKPD-Sei-1476	Si036198m.g	K4ABE1	LOC101762006
19		iEKPD-Sei-1458	Si010143m.g	K3Y7F2	LOC101762249
20		iEKPD-Sei-1439	Si022279m.g	K3Z6W0	LOC101762534
21		iEKPD-Sei-1489	Si035555m.g	K4A9J9	LOC101762678
22		iEKPD-Sei-1475	Si036229m.g	K4ABH2	LOC101763085
23		iEKPD-Sei-1435	Si010625m.g	K3Y8T3	LOC101763327
24		iEKPD-Sei-1487	Si034666m.g	K4A710	LOC101763491
25		iEKPD-Sei-1424	Si001263m.g	K3XH92	LOC101763688
26		iEKPD-Sei-1417	Si030263m.g	K3ZUI2	LOC101764263
27		iEKPD-Sei-1449	Si036008m.g	K4AAV1	LOC101764461
28		iEKPD-Sei-1422	Si022880m.g	K3Z8L0	LOC101764690
29		iEKPD-Sei-1464	Si003215m.g	K3XMU2	LOC101764774
30		iEKPD-Sei-1465	Si006636m.g	K3XXH8	LOC101765411
31		iEKPD-Sei-1498	Si029891m.g	K3ZTG1	LOC101765480
32		iEKPD-Sei-1499	Si035736m.g	K4AA30	LOC101765672
33		iEKPD-Sei-1468	Si036085m.g	K4AB28	LOC101765680
34		iEKPD-Sei-1459	Si029913m.g	K3ZTI3	LOC101765750
35		iEKPD-Sei-1413	Si036015m.g	K4AAV8	LOC101766228
36		iEKPD-Sei-1494	Si035800m.g	K4AA93	LOC101766497
37		iEKPD-Sei-1438	Si017589m.g	K3YTJ4	LOC101766543
38		iEKPD-Sei-1851	Si025857m.g	K3ZH05	LOC101768355
39		iEKPD-Sei-1416	Si001708m.g	K3XII6	LOC101768564
40		iEKPD-Sei-1436	Si030701m.g	K3ZVS0	LOC101768616
41		iEKPD-Sei-1425	Si022343m.g	K3Z723	LOC101769449
42		iEKPD-Sei-1448	Si017565m.g	K3YTH0	LOC101769507
43		iEKPD-Sei-1412	Si007044m.g	K3XYN6	LOC101770287
44		iEKPD-Sei-1460	Si010320m.g	K3Y7X9	LOC101770366
45		iEKPD-Sei-1456	Si024397m.g	K3ZCW7	LOC101770804
46		iEKPD-Sei-1483	Si019081m.g	K3YXT3	LOC101771145
47		iEKPD-Sei-1478	Si019136m.g	K3YXY6	LOC101771941
48		iEKPD-Sei-1445	Si026360m.g	K3ZIF8	LOC101771975
49		iEKPD-Sei-1486	Si019722m.g	K3YZL2	LOC101772347
50		iEKPD-Sei-1455	Si036259m.g	K4ABK2	LOC101772543
51		iEKPD-Sei-1496	Si017198m.g	K3YSF4	LOC101773144
52		iEKPD-Sei-1415	Si006734m.g	K3XXS6	LOC101773510
53		iEKPD-Sei-1434	Si001936m.g	K3XJ63	LOC101773678
54		iEKPD-Sei-1444	Si014072m.g	K3YIK2	LOC101773828
55		iEKPD-Sei-1457	Si001589m.g	K3XI67	LOC101774086
56		iEKPD-Sei-1423	Si017687m.g	K3YTU1	LOC101774627
57		iEKPD-Sei-1453	Si030278m.g	K3ZUJ7	LOC101774792
58		iEKPD-Sei-1440	Si028150m.g	K3ZNH3	LOC101774832
59		iEKPD-Sei-1430	Si006754m.g	K3XXU6	LOC101774862
60		iEKPD-Sei-1505	Si034814m.g	K4A7F8	LOC101774865
61		iEKPD-Sei-1490	Si019662m.g	K3YZF4	LOC101775047
62		iEKPD-Sei-1420	Si036123m.g	K4AB66	LOC101775133
63		iEKPD-Sei-1446	Si001741m.g	K3XIL9	LOC101775150
64		iEKPD-Sei-1481	Si009852m.g	K3Y6L1	LOC101775332
65		iEKPD-Sei-1426	Si021863m.g	K3Z5P5	LOC101777674
66		iEKPD-Sei-1472	Si022537m.g	K3Z7L7	LOC101777971
67		iEKPD-Sei-1473	Si027478m.g	K3ZLL8	LOC101778619
68		iEKPD-Sei-1356	Si002723m.g	K3XLF0	LOC101778675
69		iEKPD-Sei-1493	Si029911m.g	K3ZTI1	LOC101780075
70		iEKPD-Sei-1469	Si020423m.g	K3Z1K5	LOC101780453
71		iEKPD-Sei-1414	Si010073m.g	K3Y782	LOC101780602
72		iEKPD-Sei-1484	Si029785m.g	K3ZT55	LOC101780756
73		iEKPD-Sei-1477	Si016901m.g	K3YRK7	LOC101780970
74		iEKPD-Sei-1462	Si016697m.g	K3YR03	LOC101781126
75		iEKPD-Sei-1441	Si010194m.g	K3Y7K3	LOC101781158
76		iEKPD-Sei-1447	Si028196m.g	K3ZNL6	LOC101781690
77		iEKPD-Sei-1443	Si017490m.g	K3YT95	LOC101782036
78		iEKPD-Sei-1471	Si009847m.g	K3Y6K6	LOC101782070
79		iEKPD-Sei-1485	Si034099m.g	K4A5E5	LOC101782422
80		iEKPD-Sei-1491	Si010098m.g	K3Y7A7	LOC101782760
81		iEKPD-Sei-1451	Si036260m.g	K4ABK3	LOC101786199
82		iEKPD-Sei-1463	Si029094m.g	K3ZR64	LOC101786540
83		iEKPD-Sei-1467	Si012324m.g	K3YDL9	SETIT_012324mg
84		iEKPD-Sei-1432	Si013648m.g	K3YHD0	SETIT_013648mg
85		iEKPD-Sei-1479	Si017437m.g	A0A0Q3RLR8	SETIT_0174372mg
86		iEKPD-Sei-1495	Si019809m.g	K3YZU8	SETIT_019809mg
87		iEKPD-Sei-1470	Si027342m.g	K3ZL86	SETIT_027342mg
88		iEKPD-Sei-1466	Si028364m.g	K3ZP34	SETIT_028364mg
89		iEKPD-Sei-1474	Si033173m.g	K4A2S1	SETIT_033173mg
90		iEKPD-Sei-1488	Si035541m.g	K4A9I5	SETIT_035541mg