※ PP1 family introduction

    PP1 enzyme is composed of a catalytic subunit and a regulatory subunit(R subunit). The catalytic domain is conserved among all eukaryotes, and more than 100 regulatory subunits have been found to interact with C domain. Therefore, PP1 is a type of protein phosphatases of functional diversity which regulates a varieties of cellular processes through dephosphorylating different substrates. PP1 can promote the rational use of energy, especially when nutrients are abundant. PP1 plays a key role in the recovery from stress, however promotes apoptosis when cells are damaged beyond repair. In addition, PP1 can regulate the cell cycle (1).

Reference
1. Ceulemans, H. and Bollen, M. (2004) Functional diversity of protein phosphatase-1, a cellular economizer and reset button. Physiol Rev, 84, 1-39. PMID: 14715909

  Reviewed (9)  or Unreviewed (0) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Art-1096	AT2G29400	P30366	TOPP1
2		iEKPD-Art-1088	AT5G59160	P48482	TOPP2
3		iEKPD-Art-1092	AT1G64040	P48483	TOPP3
4		iEKPD-Art-1091	AT2G39840	P48484	TOPP4
5		iEKPD-Art-1090	AT3G46820	P48485	TOPP5
6		iEKPD-Art-1098	AT4G11240	P48486	TOPP6
7		iEKPD-Art-1097	AT5G43380	O82733	TOPP7
8		iEKPD-Art-1094	AT5G27840	O82734	TOPP8
9		iEKPD-Art-1099	AT3G05580	Q9M9W3	TOPP9