Caenorhabditis elegans      PPP/PP1


※ PP1 family introduction

    PP1 enzyme is composed of a catalytic subunit and a regulatory subunit(R subunit). The catalytic domain is conserved among all eukaryotes, and more than 100 regulatory subunits have been found to interact with C domain. Therefore, PP1 is a type of protein phosphatases of functional diversity which regulates a varieties of cellular processes through dephosphorylating different substrates. PP1 can promote the rational use of energy, especially when nutrients are abundant. PP1 plays a key role in the recovery from stress, however promotes apoptosis when cells are damaged beyond repair. In addition, PP1 can regulate the cell cycle (1).

Reference
1. Ceulemans, H. and Bollen, M. (2004) Functional diversity of protein phosphatase-1, a cellular economizer and reset button. Physiol Rev, 84, 1-39. PMID: 14715909


There are 32 genes.  Reviewed (8 or Unreviewed (24

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Cae-0509
WBGene00007354
P48458
C06A1.3
2
iEKPD-Cae-0525
WBGene00016010
P48459
C23G10.1
3
iEKPD-Cae-0543
WBGene00007763
P48460
C27B7.6
4
iEKPD-Cae-0540
WBGene00016239
P34350
C30A5.4
5
iEKPD-Cae-0476
WBGene00001747
Q27497
gsp-1
6
iEKPD-Cae-0470
WBGene00001748
P48727
gsp-2
7
iEKPD-Cae-0500
WBGene00021113
O02658
gsp-3
8
iEKPD-Cae-0493
WBGene00020187
P91420
gsp-4
9
iEKPD-Cae-0508
WBGene00015661
O16334
C09H5.7
10
iEKPD-Cae-0524
WBGene00007699
Q9U3P4
C24H11.1
11
iEKPD-Cae-0533
WBGene00007700
Q9XVD6
C24H11.2
12
iEKPD-Cae-0518
WBGene00016081
Q4R171
C25A6.1
13
iEKPD-Cae-0510
WBGene00016398
Q27475
C34D4.2
14
iEKPD-Cae-0523
WBGene00008124
Q9U3L7
C47A4.3
15
iEKPD-Cae-0519
WBGene00009054
Q27494
CELE_F22D6.9
16
iEKPD-Cae-0501
WBGene00009079
Q27495
CELE_F23B12.1
17
iEKPD-Cae-0516
WBGene00009101
Q27496
CELE_F25B3.4
18
iEKPD-Cae-0499
WBGene00009948
Q27501
CELE_F52H3.6
19
iEKPD-Cae-0507
WBGene00010265
O62272
CELE_F58G1.3
20
iEKPD-Cae-0534
WBGene00011133
Q9U395
CELE_R08A2.2
21
iEKPD-Cae-0520
WBGene00019951
Q21840
CELE_R08C7.8
22
iEKPD-Cae-0537
WBGene00020053
A0A0K3AU53
CELE_R13A5.11
23
iEKPD-Cae-0515
WBGene00011808
K8FE09
CELE_T16G12.7
24
iEKPD-Cae-0522
WBGene00012008
Q27528
CELE_T25B9.2
25
iEKPD-Cae-0535
WBGene00020985
O45001
CELE_W03D8.2
26
iEKPD-Cae-0536
WBGene00012741
Q9XW30
CELE_Y40H4A.2
27
iEKPD-Cae-0532
WBGene00013476
Q9XW33
CELE_Y69E1A.4
28
iEKPD-Cae-0513
WBGene00044347
Q4W5Q9
CELE_Y71G12B.30
29
iEKPD-Cae-0542
WBGene00022617
Q23345
CELE_ZC477.2
30
iEKPD-Cae-0514
WBGene00022710
P91569
CELE_ZK354.9
31
iEKPD-Cae-0502
WBGene00014158
G5ECL6
CELE_ZK938.1
32
iEKPD-Cae-0482
WBGene00004083
G5EC18
pph-1