Danio rerio      PPP/PP1


※ PP1 family introduction

    PP1 enzyme is composed of a catalytic subunit and a regulatory subunit(R subunit). The catalytic domain is conserved among all eukaryotes, and more than 100 regulatory subunits have been found to interact with C domain. Therefore, PP1 is a type of protein phosphatases of functional diversity which regulates a varieties of cellular processes through dephosphorylating different substrates. PP1 can promote the rational use of energy, especially when nutrients are abundant. PP1 plays a key role in the recovery from stress, however promotes apoptosis when cells are damaged beyond repair. In addition, PP1 can regulate the cell cycle (1).

Reference
1. Ceulemans, H. and Bollen, M. (2004) Functional diversity of protein phosphatase-1, a cellular economizer and reset button. Physiol Rev, 84, 1-39. PMID: 14715909


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Dar-1090
ENSDARG00000003486.6
Q6NSN6
ppp1caa
2
iEKPD-Dar-1099
ENSDARG00000071566.4
A0A0R4IW89
ppp1cab
3
iEKPD-Dar-1088
ENSDARG00000044153.6
F1QI59
ppp1cb
4
iEKPD-Dar-1091
ENSDARG00000102012.2
A0A0R4ITA1
ppp1cbl
5
iEKPD-Dar-1094
ENSDARG00000099226.2
A0A0R4IZT6
ppp1cc