Pan troglodytes      PPP/PP1


※ PP1 family introduction

    PP1 enzyme is composed of a catalytic subunit and a regulatory subunit(R subunit). The catalytic domain is conserved among all eukaryotes, and more than 100 regulatory subunits have been found to interact with C domain. Therefore, PP1 is a type of protein phosphatases of functional diversity which regulates a varieties of cellular processes through dephosphorylating different substrates. PP1 can promote the rational use of energy, especially when nutrients are abundant. PP1 plays a key role in the recovery from stress, however promotes apoptosis when cells are damaged beyond repair. In addition, PP1 can regulate the cell cycle (1).

Reference
1. Ceulemans, H. and Bollen, M. (2004) Functional diversity of protein phosphatase-1, a cellular economizer and reset button. Physiol Rev, 84, 1-39. PMID: 14715909


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Pat-0537
ENSPTRG00000049414.1
A0A2I3RYU3
2
iEKPD-Pat-0525
ENSPTRG00000038645.2
A0A2I3SF42
LOC743656
3
iEKPD-Pat-0516
ENSPTRG00000005449.6
H2Q6V7
PPP1CA
4
iEKPD-Pat-0597
ENSPTRG00000011788.6
A0A2I3RUP3
PPP1CB
5
iEKPD-Pat-0606
ENSPTRG00000005448.5
A0A2I3SL72
PPP1CC