※ PP1 family introduction

    PP1 enzyme is composed of a catalytic subunit and a regulatory subunit(R subunit). The catalytic domain is conserved among all eukaryotes, and more than 100 regulatory subunits have been found to interact with C domain. Therefore, PP1 is a type of protein phosphatases of functional diversity which regulates a varieties of cellular processes through dephosphorylating different substrates. PP1 can promote the rational use of energy, especially when nutrients are abundant. PP1 plays a key role in the recovery from stress, however promotes apoptosis when cells are damaged beyond repair. In addition, PP1 can regulate the cell cycle (1).

Reference
1. Ceulemans, H. and Bollen, M. (2004) Functional diversity of protein phosphatase-1, a cellular economizer and reset button. Physiol Rev, 84, 1-39. PMID: 14715909

  Reviewed (0)  or Unreviewed (6) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Pof-0683	ENSPFOG00000004821.2	A0A087XG98
2		iEKPD-Pof-0684	ENSPFOG00000004951.2	A0A087XGL9
3		iEKPD-Pof-0706	ENSPFOG00000007149.2	A0A087XN21
4		iEKPD-Pof-0730	ENSPFOG00000009941.2	A0A087XW45
5		iEKPD-Pof-0770	ENSPFOG00000013102.2	A0A087Y546
6		iEKPD-Pof-0790	ENSPFOG00000015626.2	A0A087YCD4