Takifugu rubripes      PPP/PP1


※ PP1 family introduction

    PP1 enzyme is composed of a catalytic subunit and a regulatory subunit(R subunit). The catalytic domain is conserved among all eukaryotes, and more than 100 regulatory subunits have been found to interact with C domain. Therefore, PP1 is a type of protein phosphatases of functional diversity which regulates a varieties of cellular processes through dephosphorylating different substrates. PP1 can promote the rational use of energy, especially when nutrients are abundant. PP1 plays a key role in the recovery from stress, however promotes apoptosis when cells are damaged beyond repair. In addition, PP1 can regulate the cell cycle (1).

Reference
1. Ceulemans, H. and Bollen, M. (2004) Functional diversity of protein phosphatase-1, a cellular economizer and reset button. Physiol Rev, 84, 1-39. PMID: 14715909


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Tar-0700
ENSTRUG00000007212.1
H2SZB7
LOC101064018
2
iEKPD-Tar-0711
ENSTRUG00000006134.1
H2SR71
LOC101069117
3
iEKPD-Tar-0709
ENSTRUG00000008801.1
H2TBS2
LOC101073968
4
iEKPD-Tar-0705
ENSTRUG00000014596.1
H2UK23
ppp1cb
5
iEKPD-Tar-0703
ENSTRUG00000015811.1
H2UTX1
PPP1CC