Sarcophilus harrisii      PPP/PP2A


※ PP2A family introduction

    PP2A, a family of PPP, is ubiquitously expressed in all eukaryotes. Three subunits compose this phosphatase holoenzyme, among which, subunit A is a 60-65 kDa structural component, B is a regulatory subunit and C is a 36-38 kDa catalytic subunit. The substrate specificity, spatial and temporal functions of PP2A is determined by regulatory subunit B. PP2A is involved in a lot of cellular processes such as cell cycle regulation, cell morphology and development. In addition, PP2A plays a critical role in regulation of specific signal transduction cascades (1).

Reference
1. Basu, S. (2011) PP2A in the regulation of cell motility and invasion. Curr Protein Pept Sci, 12, 3-11. PMID: 21190527


There are 3 genes.  Reviewed (0 or Unreviewed (3

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Sah-0560
ENSSHAG00000017845.1
G3X039
2
iEKPD-Sah-0525
ENSSHAG00000016632.1
G3WVY5
PPP2CA
3
iEKPD-Sah-0532
ENSSHAG00000008510.1
G3W324
PPP2CB