Danio rerio      PPP/PP2B


※ PP2B family introduction

    PP3, also known as Calcineurin (PP2B), is a Ca(2+)- and calmodulin-dependent Serine/Threonine protein phosphatase. PP2B shares a highly conserved catalytic subunit and heterodimeric quaternary structure from yeast to mammals. PP2B plays a important role in cellular processes and Ca(2+)-dependent signal transduction pathways, such as neurodevelopment, immune response, cardiac hypertrophy, signal transduction and muscle development (1).

Reference
1. Shi, Y. (2009) Serine/threonine phosphatases: mechanism through structure. Cell, 139, 468-484. PMID: 19879837


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Dar-1107
ENSDARG00000004988.10
A0A0R4IQG9
ppp3ca
2
iEKPD-Dar-1193
ENSDARG00000025106.8
A0A0R4IRY8
ppp3cb
3
iEKPD-Dar-1112
ENSDARG00000014962.12
A0A0R4ICR2
ppp3cca
4
iEKPD-Dar-1106
ENSDARG00000057456.6
A0A0R4IF09
ppp3ccb