※ PP2B family introduction

    PP3, also known as Calcineurin (PP2B), is a Ca(2+)- and calmodulin-dependent Serine/Threonine protein phosphatase. PP2B shares a highly conserved catalytic subunit and heterodimeric quaternary structure from yeast to mammals. PP2B plays a important role in cellular processes and Ca(2+)-dependent signal transduction pathways, such as neurodevelopment, immune response, cardiac hypertrophy, signal transduction and muscle development (1).

Reference
1. Shi, Y. (2009) Serine/threonine phosphatases: mechanism through structure. Cell, 139, 468-484. PMID: 19879837

  Reviewed (0)  or Unreviewed (3) 

No.	Status	iEKPD ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		iEKPD-Fec-0568	ENSFCAG00000022635.2	A0A2I2UWL3	PPP3CA
2		iEKPD-Fec-0590	ENSFCAG00000029907.2	M3XEV2	PPP3CB
3		iEKPD-Fec-0574	ENSFCAG00000030895.2	M3X208	PPP3CC