Homo sapiens      PPP/PP2B


※ PP2B family introduction

    PP3, also known as Calcineurin (PP2B), is a Ca(2+)- and calmodulin-dependent Serine/Threonine protein phosphatase. PP2B shares a highly conserved catalytic subunit and heterodimeric quaternary structure from yeast to mammals. PP2B plays a important role in cellular processes and Ca(2+)-dependent signal transduction pathways, such as neurodevelopment, immune response, cardiac hypertrophy, signal transduction and muscle development (1).

Reference
1. Shi, Y. (2009) Serine/threonine phosphatases: mechanism through structure. Cell, 139, 468-484. PMID: 19879837


There are 3 genes.  Reviewed (3 or Unreviewed (0

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Hos-0556
ENSG00000138814.16
Q08209
PPP3CA
2
iEKPD-Hos-0566
ENSG00000107758.15
P16298
PPP3CB
3
iEKPD-Hos-0558
ENSG00000120910.14
P48454
PPP3CC