Latimeria chalumnae      PPP/PP2B


※ PP2B family introduction

    PP3, also known as Calcineurin (PP2B), is a Ca(2+)- and calmodulin-dependent Serine/Threonine protein phosphatase. PP2B shares a highly conserved catalytic subunit and heterodimeric quaternary structure from yeast to mammals. PP2B plays a important role in cellular processes and Ca(2+)-dependent signal transduction pathways, such as neurodevelopment, immune response, cardiac hypertrophy, signal transduction and muscle development (1).

Reference
1. Shi, Y. (2009) Serine/threonine phosphatases: mechanism through structure. Cell, 139, 468-484. PMID: 19879837


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Lac-0608
ENSLACG00000004597.1
H3A6A5
2
iEKPD-Lac-0595
ENSLACG00000010549.1
H3AQR5
3
iEKPD-Lac-0589
ENSLACG00000001093.1
H2ZUZ8
PPP3CA
4
iEKPD-Lac-0605
ENSLACG00000004479.2
H3A5W6
PPP3CC