Pan troglodytes      PPP/PP2B


※ PP2B family introduction

    PP3, also known as Calcineurin (PP2B), is a Ca(2+)- and calmodulin-dependent Serine/Threonine protein phosphatase. PP2B shares a highly conserved catalytic subunit and heterodimeric quaternary structure from yeast to mammals. PP2B plays a important role in cellular processes and Ca(2+)-dependent signal transduction pathways, such as neurodevelopment, immune response, cardiac hypertrophy, signal transduction and muscle development (1).

Reference
1. Shi, Y. (2009) Serine/threonine phosphatases: mechanism through structure. Cell, 139, 468-484. PMID: 19879837


There are 3 genes.  Reviewed (0 or Unreviewed (3

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Pat-0613
ENSPTRG00000016315.5
A0A2I3RSP9
PPP3CA
2
iEKPD-Pat-0643
ENSPTRG00000002631.6
A0A2I3RJ26
PPP3CB
3
iEKPD-Pat-0614
ENSPTRG00000020059.6
A0A2I3SD30
PPP3CC