Rattus norvegicus      PPP/PP2B


※ PP2B family introduction

    PP3, also known as Calcineurin (PP2B), is a Ca(2+)- and calmodulin-dependent Serine/Threonine protein phosphatase. PP2B shares a highly conserved catalytic subunit and heterodimeric quaternary structure from yeast to mammals. PP2B plays a important role in cellular processes and Ca(2+)-dependent signal transduction pathways, such as neurodevelopment, immune response, cardiac hypertrophy, signal transduction and muscle development (1).

Reference
1. Shi, Y. (2009) Serine/threonine phosphatases: mechanism through structure. Cell, 139, 468-484. PMID: 19879837


There are 3 genes.  Reviewed (2 or Unreviewed (1

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ran-0580
ENSRNOG00000009882.7
P63329
Ppp3ca
2
iEKPD-Ran-0608
ENSRNOG00000054782.1
P20651
Ppp3cb
3
iEKPD-Ran-0585
ENSRNOG00000009745.7
E2CWF0
Ppp3cc