Verticillium dahliae      PPP/PP5


※ PP5 family introduction

    PP5 is unique member of PPP family. The most characterized feature is the presence of regulatory domain at N-terminus, TPR domain, which mediates protein-protein interactions. The phosphatase catalytic domain of PP5 is suppressed because PP5 is kept autoinhibited by TPR domain and a C-terminal helix αJ. PP5 can get its catalytic activity only if TPR domain is bound or truncated. PP5 plays an essential role in multiple cellular processes including proliferation, migration, differentiation, electrolyte balance, apoptosis, survival, and DNA damage repair (1).

Reference

1. Hinds, T.D., Jr. and Sanchez, E.R. (2008) Protein phosphatase 5. Int J Biochem Cell Biol, 40, 2358-2362. PMID: 17951098


There are 1 genes.  Reviewed (0 or Unreviewed (1

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Ved-0181
VDAG_08361
G2XDX9
VDAG_08361