Glycine max      PPP/PP6


※ PP6 family introduction

    PP6, a family of PPP, is highly conserved in evolution. PP6 is composed of a catalytic subunit, a SAPS regulatory subunit and an ankyrin repeat subunit. The three SAPS regulatory subunits are distinct in sequence and function diversity. PP6 plays an important role in signaling pathways such as NFkB signaling pathway and acts as a regulator of cell cycle progression (1). The N terminal domain can restrict G1 to S phase progression (2).

Reference
1. Mi, J., Dziegielewski, J., Bolesta, E., Brautigan, D.L. and Larner, J.M. (2009) Activation of DNA-PK by ionizing radiation is mediated by protein phosphatase 6. PLoS One, 4, e4395. PMID: 19198648
2. Stefansson, B. and Brautigan, D.L. (2007) Protein phosphatase PP6 N terminal domain restricts G1 to S phase progression in human cancer cells. Cell Cycle, 6, 1386-1392. PMID: 17568194


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Glm-2679
GLYMA_09G285800
C6TJ48
100805081
2
iEKPD-Glm-2658
GLYMA_10G288800
K7LM18
100811413
3
iEKPD-Glm-2655
GLYMA_10G288600
K7LM16
100811943
4
iEKPD-Glm-2663
GLYMA_20G100200
C6TK28
100820006