Gossypium raimondii      PPP/PP6


※ PP6 family introduction

    PP6, a family of PPP, is highly conserved in evolution. PP6 is composed of a catalytic subunit, a SAPS regulatory subunit and an ankyrin repeat subunit. The three SAPS regulatory subunits are distinct in sequence and function diversity. PP6 plays an important role in signaling pathways such as NFkB signaling pathway and acts as a regulator of cell cycle progression (1). The N terminal domain can restrict G1 to S phase progression (2).

Reference
1. Mi, J., Dziegielewski, J., Bolesta, E., Brautigan, D.L. and Larner, J.M. (2009) Activation of DNA-PK by ionizing radiation is mediated by protein phosphatase 6. PLoS One, 4, e4395. PMID: 19198648
2. Stefansson, B. and Brautigan, D.L. (2007) Protein phosphatase PP6 N terminal domain restricts G1 to S phase progression in human cancer cells. Cell Cycle, 6, 1386-1392. PMID: 17568194


There are 3 genes.  Reviewed (0 or Unreviewed (3

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Gor-1684
B456_002G015000
A0A0D2PZ16
B456_002G015000
2
iEKPD-Gor-1735
B456_005G213700
A0A0D2PX44
B456_005G213700
3
iEKPD-Gor-1883
B456_012G136400
A0A0D2S2N6
B456_012G136400