Manihot esculenta PPP/PP6
※ PP6 family introduction PP6, a family of PPP, is highly conserved in evolution. PP6 is composed of a catalytic subunit, a SAPS regulatory subunit and an ankyrin repeat subunit. The three SAPS regulatory subunits are distinct in sequence and function diversity. PP6 plays an important role in signaling pathways such as NFkB signaling pathway and acts as a regulator of cell cycle progression (1). The N terminal domain can restrict G1 to S phase progression (2). Reference
1. Mi, J., Dziegielewski, J., Bolesta, E., Brautigan, D.L. and Larner, J.M. (2009) Activation of DNA-PK by ionizing radiation is mediated by protein phosphatase 6. PLoS One, 4, e4395. PMID: 19198648
2. Stefansson, B. and Brautigan, D.L. (2007) Protein phosphatase PP6 N terminal domain restricts G1 to S phase progression in human cancer cells. Cell Cycle, 6, 1386-1392. PMID: 17568194
There are 2 genes. Reviewed (0)
or Unreviewed (2) 
※ PP6 family introduction PP6, a family of PPP, is highly conserved in evolution. PP6 is composed of a catalytic subunit, a SAPS regulatory subunit and an ankyrin repeat subunit. The three SAPS regulatory subunits are distinct in sequence and function diversity. PP6 plays an important role in signaling pathways such as NFkB signaling pathway and acts as a regulator of cell cycle progression (1). The N terminal domain can restrict G1 to S phase progression (2). Reference
1. Mi, J., Dziegielewski, J., Bolesta, E., Brautigan, D.L. and Larner, J.M. (2009) Activation of DNA-PK by ionizing radiation is mediated by protein phosphatase 6. PLoS One, 4, e4395. PMID: 19198648
2. Stefansson, B. and Brautigan, D.L. (2007) Protein phosphatase PP6 N terminal domain restricts G1 to S phase progression in human cancer cells. Cell Cycle, 6, 1386-1392. PMID: 17568194
There are 2 genes. Reviewed (0)
or Unreviewed (2) | No. | Status | iEKPD ID | Ensemble Gene ID | UniProt Accession | Gene Name |
|---|---|---|---|---|---|
| 1 | | ||||
| 2 | |