Triticum aestivum      PPP/PP6


※ PP6 family introduction

    PP6, a family of PPP, is highly conserved in evolution. PP6 is composed of a catalytic subunit, a SAPS regulatory subunit and an ankyrin repeat subunit. The three SAPS regulatory subunits are distinct in sequence and function diversity. PP6 plays an important role in signaling pathways such as NFkB signaling pathway and acts as a regulator of cell cycle progression (1). The N terminal domain can restrict G1 to S phase progression (2).

Reference
1. Mi, J., Dziegielewski, J., Bolesta, E., Brautigan, D.L. and Larner, J.M. (2009) Activation of DNA-PK by ionizing radiation is mediated by protein phosphatase 6. PLoS One, 4, e4395. PMID: 19198648
2. Stefansson, B. and Brautigan, D.L. (2007) Protein phosphatase PP6 N terminal domain restricts G1 to S phase progression in human cancer cells. Cell Cycle, 6, 1386-1392. PMID: 17568194


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusiEKPD IDEnsemble Gene IDUniProt AccessionGene Name
1
iEKPD-Tra-4825
TRIAE_CS42_1AL_TGACv1_002758_AA0044950
W4ZSW9
2
iEKPD-Tra-4841
TRIAE_CS42_1BL_TGACv1_032451_AA0130050
A0A1D5SF42
3
iEKPD-Tra-4863
TRIAE_CS42_1DL_TGACv1_062226_AA0210930
A0A1D5SVD2
4
iEKPD-Tra-4937
TRIAE_CS42_3AL_TGACv1_194993_AA0643280
A0A077RTW4
TRAES_3BF011700090CFD_c1